CollaGEN | Connective Tissue & Joint Support | Calabasas Medicine Group

Collagen is the most abundant structural protein found in the skin and connective tissues of the body. Roughly 29 different types have been identified with 90% consisting of type I and type II collagen. Type I collagen is found within the tendons, ligaments, fascia, skin, bones, organs, heart valves and blood vessels. Type II collagen is found within 70% of the body's cartilaginous mass, which includes hyaline and articular cartilage, and the intervertebral discs. Over time, factors such as age, lifestyle, genetics, previous injury, inflammation and biomechanical instability can lead to the breakdown of collagen and slow the process of healthy collagen synthesis.

CollaGEN includes three clinically studied ingredients to support the natural healing process and maintain connective tissue structure. Most therapies simply block joint pain and connective tissue discomfort from exercise, and in doing so inhibit the regeneration and elongation of specific polysaccharide precursors and deplete nutrients, such as magnesium and vitamin C, that maintain joint and connective tissue health. FORTIGEL®, Tendaxion® and Mobilee® protect and preserve cartilage, tendons, ligaments, fascia, bone and the intervertebral discs of the spine.

FORTIGEL®, backed by more than fifteen studies, provides highly concentrated bioactive collagen peptides (BCPs), which have been proven to stimulate chondrocytes to produce proteoglycans and type II collagen. This collagen has been hydrolyzed to provide short-chain peptides with a low molecular weight to allow for easier absorption, transport and accumulation within the target connective tissue. FORTIGEL® provides 5 g hypoallergenic protein per serving from a sustainable protein source. This lower dose decreases excess oxalate production compared to higher-dose collagen and gelatin products.

Mobilee®, sourced from rooster comb, is patented to provide the highest concentration of hyaluronic acid (HA) for easy absorption. This extract also contains collagen and polysaccharides to aid in the viscoelastic and lubricating properties of HA.

Tendaxion® is a combination of mucopolysaccharides and type I collagen, which provides structural support to tendons, ligaments, fascia, skin and bones. The molecular structure and organization of the collagen fibers are key determinants in the ability of these connective tissues to endure mechanical force and fuel self-repair. While collagen provides much of the structure and strength to connective tissues, mucopolysaccharides help maintain structural integrity, lubrication and spacing of collagen fibers. Furthermore, mucopolysaccharides have been shown to increase collagen and non-collagenous protein synthesis in cultures of bovine tenocytes and ligament fibroblasts.