Orthomega | Omega-3 Fish Oil | Calabasas Medicine Group
Vitamins & Supplements Program
Orthomega
Omega-3 Fish Oil
Clinical Applications
- •Supports Cardiovascular Health
- •Promotes Healthy Inflammatory Balance
- •Supports Cognitive Function and Brain Health
- •Maintains Healthy Triglyceride Levels Already Within Normal Range
- •Supports Joint Comfort and Mobility
Orthomega provides a highly concentrated source of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the preferred triglyceride form for optimal absorption. Each softgel delivers 820 mg of EPA and 550 mg of DHA, sourced from cold-water fish and purified to remove heavy metals, PCBs, and other environmental contaminants.
Omega-3 fatty acids are essential fats that the body cannot synthesize on its own and must be obtained through diet or supplementation. EPA and DHA play critical roles in cardiovascular function, brain health, inflammatory regulation, and cellular membrane integrity throughout the body.
Overview
Omega-3 polyunsaturated fatty acids (PUFAs) are a family of long-chain fats that serve as structural components of cell membranes and as precursors to bioactive lipid mediators that regulate inflammation, immune function, and vascular tone. The two most clinically significant omega-3s are EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), both of which are found primarily in cold-water marine fish.
The modern Western diet is characterized by a high ratio of omega-6 to omega-3 fatty acids — often exceeding 15:1 — compared to the ancestral ratio of approximately 4:1 or lower. This imbalance promotes a pro-inflammatory state that is associated with increased risk of cardiovascular disease, metabolic dysfunction, and cognitive decline. Supplementation with concentrated EPA and DHA helps restore a healthier omega-6 to omega-3 ratio and supports the body's natural inflammatory resolution pathways.
Orthomega uses fish oil in the re-esterified triglyceride (rTG) form, which research has shown to be absorbed approximately 70% more efficiently than the ethyl ester (EE) form commonly found in lower-quality fish oil supplements. This superior bioavailability ensures that patients receive the full therapeutic benefit of each dose.
Benefits
EPA (Eicosapentaenoic Acid)
Eicosapentaenoic acid (EPA) is a 20-carbon omega-3 fatty acid that serves as a precursor to a class of anti-inflammatory eicosanoids, including prostaglandins of the 3-series and leukotrienes of the 5-series. These lipid mediators help modulate the body's inflammatory response and support vascular health. EPA has been shown in numerous clinical trials to support healthy triglyceride levels already within the normal range, promote healthy blood pressure, and support cardiovascular function. EPA also plays a role in supporting mood and emotional well-being by influencing neurotransmitter signaling pathways.
DHA (Docosahexaenoic Acid)
Docosahexaenoic acid (DHA) is a 22-carbon omega-3 fatty acid that is the most abundant structural fat in the brain and retina. DHA is a critical component of neuronal cell membranes, where it supports membrane fluidity, receptor function, and synaptic transmission. Adequate DHA levels are essential for cognitive function, memory, and visual acuity across all life stages. DHA also contributes to cardiovascular health by supporting healthy heart rhythm, endothelial function, and platelet aggregation. Research has demonstrated that DHA supplementation supports cognitive performance and may help maintain brain health with aging.
Triglyceride Form & Purity
The form in which omega-3 fatty acids are delivered significantly affects their absorption and clinical efficacy. Orthomega uses fish oil in the re-esterified triglyceride (rTG) form, which closely mirrors the natural structure of omega-3s found in whole fish. Studies have demonstrated that rTG fish oil is absorbed approximately 70% more efficiently than the ethyl ester form. Orthomega is also manufactured to the highest purity standards, with each batch tested for heavy metals (mercury, lead, cadmium, arsenic), PCBs, dioxins, and other environmental contaminants to ensure safety and quality.
Supplement Facts
Serving Size: 1 Softgel | Servings Per Container: 60
| Ingredient | Amount Per Serving | % Daily Value |
|---|---|---|
| Calories | 10 | |
| Total Fat | 1 g | 1% |
| Fish Oil Concentrate (as re-esterified triglycerides) | 1,400 mg | * |
| EPA (Eicosapentaenoic Acid) | 820 mg | * |
| DHA (Docosahexaenoic Acid) | 550 mg | * |
| Other Omega-3 Fatty Acids | 30 mg | * |
* Daily Value not established. † Percent Daily Values are based on a 2,000 calorie diet.
Other Ingredients
Gelatin (Bovine), Glycerin, Purified Water, and Natural Lemon Flavor.
Directions
1–2 softgels per day with meals or as recommended by your health care professional.
Does Not Contain
Gluten, corn, yeast, artificial colors or flavors.
Cautions
Do not consume this product if you are pregnant or nursing. Consult Dr. Cohen for further information. As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult Dr. Cohen if you have negative reactions upon ingestion.
Source: The information was obtained from Ortho Molecular Products.